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Analysis Study Research Paper | Radiology and Medical Imaging Sciences | India | Volume 14 Issue 1, January 2025 | Popularity: 4.7 / 10

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Ultrasound Shear Wave Elastographic Evaluation of Liver in Non-Alcoholic Fatty Liver Disease: A Hospital-Based Cross-Sectional Study

Dr. Mihir Joshi, Dr. N. U. Bahri, Dr. Juhi Porecha

Abstract: Background: Non-Alcoholic Fatty Liver Disease (NAFLD) is a major cause of chronic liver disease, particularly in South Asia, with significant progression risks to fibrosis, cirrhosis, and hepatocellular carcinoma. Shear Wave Elastography (SWE) is a non-invasive alternative to liver biopsy for assessing liver stiffness and detecting fibrosis. Objective: To evaluate the utility of SWE in identifying liver fibrosis in NAFLD patients and to analyse associated risk factors in the Saurashtra population. Methods: A cross-sectional study was conducted on 100 NAFLD patients from September 2022 to September 2023. Patients underwent B-mode ultrasound and SWE using Samsung RS80A with Prestige. Liver stiffness was categorized into normal (<5.7 kPa), dysfunction (<8 kPa), and fibrosis (>8 kPa). Risk factors such as age, BMI, diabetes, and hypertension were examined. Results: Liver dysfunction or fibrosis was observed in 34% of patients, with 9% showing significant fibrosis (>8 kPa). Risk Factors: 1) Obesity (BMI > 25): 58% of fibrosis cases (OR = 7.9). 2) Diabetes: 57% of fibrosis cases (OR = 3.3). 3) Age >60 years: 41% of fibrosis cases (OR = 1.8). 4) Higher grades of fatty liver correlated with increased fibrosis, though the association was not statistically significant (p = 0.13). Conclusion: SWE is a reliable, non-invasive diagnostic tool for detecting liver fibrosis in NAFLD patients. It highlights the importance of addressing modifiable risk factors such as obesity and diabetes to prevent progression to irreversible liver damage. Multi-center and longitudinal studies are recommended for further validation.

Keywords: Non-Alcoholic Fatty Liver Disease, Shear Wave Elastography, Liver Fibrosis, Obesity, Diabetes, Ultrasound Imaging, Saurashtra Population

Edition: Volume 14 Issue 1, January 2025

Pages: 69 - 71

DOI: https://www.doi.org/10.21275/SR241229222507

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