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Research Paper | Medical Science | Volume 13 Issue 1, January 2024 | Pages: 1583 - 1587 | India
Study of Serum Creatinine and Serum Uric Acid in Subclinical and Overt Hypothyroid Patients
Abstract: Background: The relationship between hypothyroidism and kidney dysfunction is complex.The paucity of Indian data highlighting the effect of inadequate thyroid hormones on renal function led us to study in order to examine potential mechanistic links between thyroid and kidney disease in this sub-population. To study Serum creatinine and Serum Uric acid and correlate with TSH,FT3,FT4 in subclinical and overt hypothyroid patients. Material and Methods: A Cross-Sectional Study was conducted on patients who are diagnosed with hypothyroidism in OPD of the Department of General Medicine of ESIC MC, Rajajinagar Bangalore-10. Study was conducted on 96 Hypothyroid patients. Serum TSH, FT3, FT4 were analysed by using chemiluminescence immunoassay from Beckman coulter. Serum Creatinine by modified Jaffe?s method, Serum Uric acid by uricase method were analysed using COBAS INTEGRA 400 PLUS. Results: In our study there is statistically significant, positive correlation between S.Creatinine and TSH in hypothyroid groups (R=0.60, p=
Keywords: Hypothyroidism, Creatinine, Uric acid
How to Cite?: M. S. Yamini, Simant Baliar Singh, "Study of Serum Creatinine and Serum Uric Acid in Subclinical and Overt Hypothyroid Patients", Volume 13 Issue 1, January 2024, International Journal of Science and Research (IJSR), Pages: 1583-1587, https://www.ijsr.net/getabstract.php?paperid=SR24125221520, DOI: https://dx.doi.org/10.21275/SR24125221520