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Case Studies | Medicine | India | Volume 13 Issue 2, February 2024 | Rating: 5 / 10

A Case Report on Inhaled Budesonide Induced Addison's Disease

Dr. Erin Xavier | Breezy Ani Sam ^[2] | Elisaba Jacob | Dr. Mohan Varghese ^[5]

Abstract: Addison's disease (AD) also called as hypoadrenalism is a rare disorder of adrenal gland characterized by inadequate production of steroid hormones: cortisol and aldosterone and is presented with both oral and systemic manifestation. The symptoms of the disease include hyperpigmentation of skin and mucosa, weakness, abdominal pain, weight loss. In our study a 67-year-old male patient presented with complaints of multiple episodes of vomiting, generalized tiredness, decreased appetite, hyponatremia and hyperpigmentation of skin, regions of tongue, palms and feet which is considered as the hallmark sign of AD and patient was only on Inhaler Foracort (Budesonide + Formetrol) taken for his breathing difficulty occasionally for past 20 years. By analyzing the Subjective and Objective evidence the patient was suspected to have BUDESONIDE INDUCED ADDISON'S DISEASES which was further confirmed by Naranjo ADR Probability Scale Score and WHO -UMC Causality Assessment Scale.

Keywords: Addison's disease, Hyponatremia, Budesonide

Edition: Volume 13 Issue 2, February 2024,

Pages: 913 - 915