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Research Proposals or Synopsis | Hematology | Congo (DRC) | Volume 13 Issue 4, April 2024 | Rating: 5.1 / 10
Hemogram Abnormalities Associated with the Severity of COVID 19 in Patients at the University Clinics of Kinshasa
Mamy Mbelu | Didine Kaba | Mireille Nganga | Gustave Ilunga | Benjamin Longo - Mbenza | Jean - Jacques Malemba
Abstract: Context: COVID 19 is a pathology related to SARS Cov 2. Affected patients may present with blood count abnormalities, including lymphopenia and neutrophilia. Object: To identify blood count abnormalities associated with the severity of COVID 19. Methods: This is a cross - sectional study conducted in the clinical biology department at University Hospital of Kinshasa (UHK). It covers the period from June to September 2020. All COVID 19 patients tested positive by PCR were included. The parameters of interest were the clinical characteristics of the patients, the hemogram parameters and the neutrophils lymphocytes ratio (NLR). Results: Sixty - two patients were included of whom 40 were men (64.5%). The M/F sex ratio was 2. Their average age was 53.3?16.3 years. The main complaints were cough (67.7%), fever (51.6%) and asthenia (30.6%). The average SaO2 was 83.2?14.7%; and 77.4% of patients had SaO2<95%. Compared to survivors, deceased patients had a significantly lower average SaO2 (p<0.001). The majority of patients were in the severe stage (61.3%). Twenty - one patients (33.9%) died. Patients with severe Covid 19 represented 90.5% of deaths and 46.3% of survivors (p=0.00). Deceased patients had significantly lower hemoglobin averages (p=0.023), higher median WBC and NLR. Anemia, NLR ?7 and SaO2<95% were significantly associated with the risk of death in COVID - 19 patients. Conclusion: This study showed that certain hematological parameters are predictors of poor prognosis in patients with a severe form of Covid19. Physicians should seek them for a better care of our patients.
Keywords: Covid - 19, hemogram abnormalities, Kinshasa
Edition: Volume 13 Issue 4, April 2024,
Pages: 1136 - 1144