International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064




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Experimental Result Paper | Dentistry | India | Volume 13 Issue 5, May 2024 | Rating: 5.1 / 10


Quantitative Assessment of Pulp Tissue Dissolution after Exposure to 5.25% Sodium Hypochlorite at 1min, 5min, and 60min at 37 ?C and 60 ?C.

Dr. Aditi Pande | Dr. Pratima Shenoi [2] | Dr. Mohit Gunwal | Dr. Shriya Shahu | Dr. Gautam Badole | Dr. Rajesh Kubde


Abstract: Context: The success of endodontic treatment mainly depends on effective irrigation methods to dissolve pulpal tissue, remove debris, and clean the complex root canal system. Sodium hypochlorite (NaOCI) is a widely used endodontic irrigant due to its tissue - dissolving and antibacterial properties. Aim: Quantitative evaluation of human pulp tissue dissolution at different temperatures of sodium hypochlorite. Materials and Methods: Twenty - four samples of human pulp tissue were collected from freshly extracted premolars. The samples were divided into two groups: Group I with normal saline and Group II with 5.25% NaOCI. Each group was further divided into two subgroups according to temperature (37?C and 60?C) and three divisions based on time intervals of tissue dissolution (1 minute, 5 minutes, and 60 minutes). Result: The results showed that normal saline did not show any dissolution of pulp tissue. In contrast, 5.25% NaOCl demonstrated a significantly higher tissue dissolution capacity compared to normal saline at both temperatures and all - time intervals. Less pulp dissolution was seen when kept in contact for 1 minute but increased subsequently when kept in contact for 5 minutes to 60 minutes at 60?C. Conclusion: According to the findings of the current study, it can be concluded that 5.25% NaOCl exhibits maximum pulp tissue dissolution at 60?C temperature when kept in contact with pulpal tissue for a minimum of 5 minutes and a maximum of 60 minutes.


Keywords: endodontic irrigation, sodium hypochlorite, pulp tissue dissolution, temperature effects, time intervals


Edition: Volume 13 Issue 5, May 2024,


Pages: 639 - 645


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