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Case Studies | Medicine | India | Volume 13 Issue 5, May 2024 | Popularity: 5.2 / 10

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Unraveling the Clinical Conundrum: A Multifaceted Case Report in a Young Female with Situs Inversus, Chronic Sinusitis and Bronchiectasis

Dr. Anbalagan Suyambulingam

Abstract: Background: A 25 - year - old female presented with a chief complaint of dry cough persisting for two months. Accompanying symptoms included recurrent severe headaches over six months. Notably, the patient had a history of situs inversus diagnosed four years prior and had been married for three years without children. Initial evaluation revealed chronic sinusitis on CT paranasal sinuses and dextrocardia with normal left ventricular function on 2D echocardiography. Pulmonology consultation was sought due to persistent cough, leading to the discovery of bronchiectasis on high - resolution CT (HRCT) chest. Additionally, the patient reported infertility. Method: A comprehensive clinical examination, including ENT and pulmonology consultations, was conducted. Imaging modalities such as CT paranasal sinuses, 2D echocardiography, and HRCT chest were employed for diagnostic purposes. Relevant medical history, physical examination findings, and diagnostic results were systematically analyzed to establish a comprehensive understanding of the patient's condition. Results: The patient's evaluation revealed chronic sinusitis and bronchiectasis, concurrent with situs inversus and dextrocardia. Despite the absence of weight loss, fever, or other significant symptoms, the persistence of dry cough warranted further investigation. Imaging studies provided crucial insights into the structural abnormalities contributing to the patient's respiratory symptoms and infertility. Conclusion: Ultimately, the constellation of findings in this case, including situs inversus, dextrocardia, chronic sinusitis, bronchiectasis, and infertility, led to the diagnosis of Kartagener's syndrome. This rare genetic disorder underscores the importance of recognizing complex anatomical variations and their potential impact on both respiratory and reproductive health. Early diagnosis and multidisciplinary management are crucial in mitigating complications and improving patient outcomes in Kartagener's syndrome. Further research into its pathogenesis and optimal therapeutic interventions is warranted to enhance clinical care for affected individuals.

Keywords: dry cough, chronic sinusitis, situs inversus, bronchiectasis, Kartagener's syndrome

Edition: Volume 13 Issue 5, May 2024

Pages: 1426 - 1428

DOI: https://www.doi.org/10.21275/SR24523145844

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