Hypochloremia in Patients with Severe Traumatic Brain Injury at a Tertiary Care Hospital in India: A Possible Threat for Mortality

Shoeb Khan, Ugan Singh Meena

Abstract: Objective: To evaluate the correlation between Individuals with severe traumatic brain injury and death from electrolyte imbalance. Methodology: In a prospective cohort study, patient records suffering from a severe brain injury caused by trauma Glasgow Coma Scale score less than 8, and electrolyte abnormalities were reviewed. To determine a correlation between the patients who passed away and the ones who lived, electrolyte levels were examined. For categorical variables, bivariate analysis was carried out using the ?2 test, which has a 95% statistical accuracy. To ascertain the correlation between electrolyte fluctuations and mortality, the ?2 test was employed in conjunction with multiple comparisons. The linkage between fatalities and electrolyte shifts was analyzed using logistic regression. 95 percent of statistical tests were reliable. Results: In 24.5 % of patients who passed away, Elevated mortality risk was significantly correlated with hypochloremia (P 0.03). It also represents the substantial link between The Examination of Acute Physiology and Chronic Health APACHE II (P < 0.01) and age (P < 0.01). Conclusion: Hypochloremia may be a significant prognostic factor for determining death in individuals suffering from severe TBI risk and optimizing treatment.

Keywords: severe traumatic brain injury, electrolyte imbalance, hypochloremia