Schizophrenia: Stress and Neuroleptics: What Support?

Kaarar Narjess, Bairi Abdel Majid, Boudef Mohamed, Tahraoui Abdel Karim

Abstract: This work is primarily due to describe abnormalities of the HPA axis in schizophrenic patients, after the administration of dexamethasone (0, 5 mg), and secondarily to determine the action of Neuroleptics (terms of prescription) on stress. Our research included 18 male schizophrenic patients, admitted to the psychiatric Emergency Department. The result of the dexamethasone suppression test revealed a large amount of no suppression of cortisol after DST (44 %), also, the neuroleptic treatment has not influenced anomalies of the test, or the decrease in the level of stress in these patients. These results support idea that schizophrenics are hyper stressed, and unfortunately they are not treated as they should be. We also affirm that the efficacy of antipsychotic treatment depends on the quality of the work does the practitioner with the patient, and its support.

Keywords: schizophrenia, suppression test of dexamethasone, cortisol, neuroleptic, support, psychiatric hospital