Ameliorative Effects of Methanolic Extract of Sennaalataleaves on Streptozotocin (Stz)-Induced Oxidative Stress and Hepatotoxicity in Adult Wistar Albinorats

Akintola A.O, Adedosu O.T, Kehinde B.D, Ibikunle G.J

Abstract: Introduction Sennaalata leaf is widely available in the tropics and has very important applications in folkloric medicine. It contains several biological properties and antioxidant properties. In the northern part of Nigeria, particularly in Adamawa and Taraba States, the root, stem and leaves are used by practitioners of herbal medicines to treat burns, skin and wound infections, diarrhea, gastrointestinal and upper respiratory tract infections.

Keywords: Oxidative stress, Streptozotocin, Sennaalata leaves, hepatoprotective effects, wistar albino rats